Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

677
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
677
Cancer Vaccines01:30

Cancer Vaccines

523
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
523

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tailored Biomaterials Induce Tertiary Lymphoid Structures for Boosting Cancer Immunotherapy.

ACS nano·2026
Same author

FSTL3-Driven Cuproptosis Resistance and EPCs Promote OSCC Metastasis.

Journal of dental research·2026
Same author

Multi-omics approaches reveal erythroid progenitor cell in cancer: from passive bystander to active player.

Oncogene·2026
Same author

Triple-Cascade Responsive Pneumatic Nanomotor Enhance Cancer Immunotherapy by Oncolytic Virus-Triggered Pyroptosis.

ACS nano·2026
Same author

Engineered covalent organic framework-based nanosystem for strengthening pyroptosis-mediated tumor immunotherapy.

Chemical communications (Cambridge, England)·2026
Same author

Initiation of Tertiary Lymphoid Structures for Cancer Immunotherapy.

Research (Washington, D.C.)·2026

Related Experiment Video

Updated: Sep 20, 2025

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles
08:35

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles

Published on: January 4, 2012

28.4K

Bioengineered nanogels for cancer immunotherapy.

Xianbin Ma1, Shu-Jin Li2, Yuantong Liu2

  • 1State Key Laboratory of Silkworm Genome Biology, School of Materials and Energy & Chongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, Southwest University, Chongqing 400715, China. zgxu@swu.edu.cn.

Chemical Society Reviews
|June 6, 2022
PubMed
Summary

Nanogels offer a promising platform for cancer immunotherapy, improving drug delivery and enhancing anti-tumor immunity. These nanocarriers overcome limitations of traditional immunotherapy by improving tumor penetration and reducing side effects.

More Related Videos

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

1.2K
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

16.8K

Related Experiment Videos

Last Updated: Sep 20, 2025

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles
08:35

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles

Published on: January 4, 2012

28.4K
Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

1.2K
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

16.8K

Area of Science:

  • Biomedicine
  • Nanotechnology
  • Immunology

Background:

  • Nanogels are biocompatible, stable, and low-toxicity nanocarriers for drug delivery.
  • Immunotherapy is a key cancer treatment strategy, but faces challenges like low response rates and adverse events.
  • Nanogels, despite initial low enrichment, show potential to overcome nanomedicine limitations in cancer treatment.

Purpose of the Study:

  • To review recent advances in nanogel-based cancer immunotherapy.
  • To highlight nanogel applications in delivering immunomodulatory agents and enhancing anti-tumor immunity.
  • To discuss future prospects and challenges for nanogel immunotherapy in clinical settings.

Main Methods:

  • Literature review of nanogel-based immunotherapy strategies.
  • Analysis of nanogel properties for drug delivery and immune system modulation.
  • Summarization of nanogel applications in targeting, vaccine development, and CAR-T cell therapy.

Main Results:

  • Nanogels enhance tumor penetration and accumulation due to their stability and circulation time.
  • Stimuli-responsive functional groups on nanogels reduce off-target effects and improve drug bioavailability.
  • Nanogels facilitate slow drug release, prolonging immune system activation and therapeutic effects.

Conclusions:

  • Nanogel-based immunotherapy is an effective strategy for cancer treatment.
  • Nanogels can deliver various immunomodulatory agents and enhance anti-tumor immune responses.
  • Further research is needed to address challenges and realize the clinical potential of nanogel immunotherapy.