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Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging
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Split-Window OCT biometry in pseudophakic eyes.

Bartosz L Sikorski1, Kenneth J Hoffer2,3

  • 1Department of Ophthalmology, Nicolaus Copernicus University, Toruń, Poland.

Acta Ophthalmologica
|June 7, 2022
PubMed
Summary
This summary is machine-generated.

Split-Window optical coherence tomography (SW-OCT) biometry accurately measures ocular dimensions in pseudophakic eyes, showing high agreement with SS-OCT. SW-OCT also demonstrated lower failure rates for anterior chamber depth and IOL thickness measurements.

Keywords:
OCTSW-OCTSplit-Window OCTbiometrypseudophakic eyes

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Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Medical Imaging

Background:

  • Accurate biometry is crucial for intraocular lens (IOL) power calculation.
  • Pseudophakic eyes present unique challenges for ocular biometry due to the presence of an IOL and potential posterior capsule opacification.

Purpose of the Study:

  • To evaluate the utility of Split-Window optical coherence tomography (SW-OCT) for measuring axial dimensions, IOL, and posterior capsule in pseudophakic eyes.
  • To compare SW-OCT biometry with spectral-domain OCT (SD-OCT) and swept-source OCT (SS-OCT) biometry.

Main Methods:

  • Sixty-nine pseudophakic eyes were analyzed using SW-OCT (REVO NX, Optopol Technology).
  • Measurements were compared to those obtained with an SS-OCT-based biometer (IOLMaster 700, Carl Zeiss Meditec).
  • Agreement was assessed using paired t-tests, intraclass correlation coefficients (ICC), and Bland-Altman plots.

Main Results:

  • SW-OCT showed very high correlation with SS-OCT for axial length (ICC=1.000), anterior chamber depth (ACD) (ICC=0.997), IOL thickness (IOL LT) (ICC=0.997), and central corneal thickness (CCT) (ICC=0.987).
  • Mean differences were minimal for AL (0.003 ± 0.021 mm), ACD (-0.009 ± 0.025 mm), and IOL LT (0.001 ± 0.021 mm).
  • SW-OCT exhibited significantly lower failure rates for ACD and IOL LT measurements compared to SS-OCT.

Conclusions:

  • SW-OCT provides accurate biometric measurements in pseudophakic eyes with high agreement to SS-OCT.
  • SW-OCT offers improved reliability for ACD and IOL LT measurements due to lower failure rates.
  • High-resolution SW-OCT imaging facilitates precise assessment of IOL position and visualization of posterior capsule changes.