Related Experiment Video
Updated: Sep 20, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
The emergence of dengue as a virological challenge: from phantom disease to "pet" endemic, 1986-1987
1Doutorando, Programa de Pós-graduação de História das Ciências e da Saúde/Casa de Oswaldo Cruz/Fiocruz. Rio de Janeiro - RJ - Brasil jorge.tibilletti@gmail.com.
Abstract:
This article analyzes how dengue presented a virological challenge during the 1980s in order to explore the role of virological studies in understanding this disease and constructing expertise in arboviral diseases. Although outbreaks were reported throughout the twentieth century, dengue was barely known in the Americas until the epidemic of dengue fever in Cuba in 1981. When the disease reached the Brazilian city of Nova Iguaçu (RJ) in 1986, it became the focus of attention for a team of virologists led by Hermann Schatzmayr, who mobilized efforts after the creation of the Flavivirus Laboratory at the Oswaldo Cruz Institute.

