Anastomosing hemangioma: a current update on clinical, pathological and imaging features

Area of Science:

• Vascular Neoplasms
• Oncology
• Pathology

Background:

• Anastomosing hemangioma (AH) is a rare, benign vascular neoplasm.
• AH commonly affects the kidneys, gonads, and retroperitoneal tissues, particularly in end-stage renal disease.
• Molecular pathogenesis is linked to activating mutations in GNA genes.

Purpose of the Study:

• To provide an updated review of anastomosing hemangioma.
• To cover clinical, pathological, and imaging characteristics of AH.

Main Methods:

• Literature review of recent studies on anastomosing hemangioma.
• Synthesis of clinical, pathological, and imaging data.

Main Results:

• AH presents as a solitary, well-circumscribed, hypervascular tumor.
• The tumor follows a benign course with an excellent prognosis.
• Kidney involvement is most common, often associated with end-stage renal disease.

Conclusions:

• Anastomosing hemangioma is a distinct benign vascular tumor with specific genetic drivers.
• Understanding its features is crucial for accurate diagnosis and management.