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Updated: Sep 8, 2025

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

Spinning-enabled wireless amphibious origami millirobot.

Qiji Ze¹, Shuai Wu¹, Jize Dai¹

¹Department of Mechanical Engineering, Stanford University, Stanford, CA, 94305, USA.

Nature Communications

|June 14, 2022

Summary

This summary is machine-generated.

This study introduces a new magnetically actuated amphibious origami millirobot. This innovative device offers wireless, multi-modal locomotion and cargo delivery for potential biomedical applications.

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Area of Science:

Robotics
Biomedical Engineering
Materials Science

Background:

Millimeter-scale origami robots show promise for biomedical applications.
Current designs often lack integrated locomotion and functional components.
Existing devices struggle with amphibious (on-ground and in-water) locomotion.

Purpose of the Study:

To develop a magnetically actuated amphibious origami millirobot.
To integrate multimodal locomotion, liquid medicine delivery, and cargo transportation.
To enable wireless operation for biomedical applications.

Main Methods:

Utilizing Kresling origami (triangulated hollow cylinder) for geometric features and folding/unfolding.
Employing magnetic actuation for wireless control.
Exploiting spinning motion for propulsion, pumping, and cargo suction.

Main Results:

Demonstrated omnidirectional locomotion (rolling, flipping, spinning) in various environments.
Achieved controlled delivery of liquid medicine via folding/unfolding mechanism.
Enabled targeted solid cargo transportation using spinning-induced suction.

Conclusions:

The developed millirobot integrates multiple functions including amphibious locomotion and cargo handling.
This technology has potential as a minimally invasive device for biomedical diagnoses and treatments.
Further development could lead to advanced robotic solutions in healthcare.