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Donor plasmapheresis: a comparative study using four different types of equipment.
The International Journal of Artificial Organs
|January 1, 1987
Summary
Automated plasmapheresis using single-needle technology is feasible and well-tolerated by healthy volunteers. This study compared four equipment types for plasma harvesting efficiency and safety.
Area of Science:
- Medical Science
- Biotechnology
Background:
- Automated plasmapheresis is a method for collecting plasma from donors.
- Evaluating different equipment is crucial for optimizing blood collection procedures.
Purpose of the Study:
- To assess the feasibility of single-donor plasma harvesting.
- To evaluate donor acceptability, speed, economy, and safety of four plasmapheresis devices.
- To determine the quality of harvested plasma.
Main Methods:
- 106 healthy volunteers participated in the study.
- Automated plasmapheresis was performed using four single-needle systems: PCS, FILTRA, PLASMAPUR, and AUTOPHERESIS CTM.
- Donor tolerance and laboratory values were monitored.
Main Results:
- All four single-needle plasmapheresis systems were feasible for plasma harvesting.
- Procedures were well-tolerated by donors.
- No significant changes in pre- and post-procedure laboratory values were observed.
Conclusions:
- Single-needle automated plasmapheresis is a safe and acceptable procedure for healthy volunteers.
- The evaluated equipment demonstrated feasibility for efficient plasma collection.