Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sperm Structure and Semen Composition01:22

Sperm Structure and Semen Composition

4.9K
During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...
4.9K
Infertility in Males01:23

Infertility in Males

330
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
330
Spermatogenesis01:41

Spermatogenesis

103.2K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
103.2K
Sperm Transport01:15

Sperm Transport

1.3K
The journey of sperm from its origin to the point of ejaculation begins within the seminiferous tubules of the testis. Here, Sertoli cells produce fluid that propels non-motile sperm through a series of conduits, starting with the straight tubules leading to the rete testis. This interconnected network of tubules acts as the initial pathway for sperm, guiding them into the efferent ductules and then into the epididymis for maturation.
The maturation phase occurs in the epididymis, where sperm...
1.3K
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

15.8K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
15.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishment and Preliminary Application of a Multiplex TaqMan Real-Time Fluorescence Quantitative PCR Assay for the Detection of <i>Pneumocystis</i> Species.

Microorganisms·2026
Same author

Association of IL-10 promoter and IL-12 gene polymorphisms with the risk of symptomatic Helicobacter pylori infection.

BMC gastroenterology·2026
Same author

Integrated Protein Precipitation-Solid-Phase Extraction Workflow for Deep Top-Down Proteomic Analysis of Human Serum.

Journal of proteome research·2026
Same author

Efficient amyloid-β degradation in Alzheimer's disease using SPYTACs.

Cell·2026
Same author

F-53B triggers ovarian granulosa cell senescence and ovarian dysfunction by triggering mitochondrial dysfunction.

Chemico-biological interactions·2025
Same author

The effects of opium consumption on glycemic indices: a systematic review and meta-analysis of human and animal studies.

BMC pharmacology & toxicology·2025
Same journal

Recombinant LH supplementation during ovarian stimulation modulates early embryo morphokinetics without affecting IVF outcomes in normal responders: a retrospective time-lapse study.

Journal of assisted reproduction and genetics·2026
Same journal

Redefining success in assisted reproductive technologies: the Embryo-Maternal-Offspring Continuum Framework.

Journal of assisted reproduction and genetics·2026
Same journal

Anti-Müllerian hormone and somatic ovarian function: a new perspective.

Journal of assisted reproduction and genetics·2026
Same journal

Rethinking supply chain disruption: a practical resilience framework for IVF laboratory quality management.

Journal of assisted reproduction and genetics·2026
Same journal

Another round, another chance: oocyte developmental competence and outcomes in second IVF attempts-the earlier, the better.

Journal of assisted reproduction and genetics·2026
Same journal

Fertility knowledge and family planning perspectives among female physicians: a cross-sectional study.

Journal of assisted reproduction and genetics·2026
See all related articles

Related Experiment Video

Updated: Sep 7, 2025

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
08:48

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects

Published on: April 21, 2022

2.7K

SARS-CoV-2 effects on sperm parameters: a meta-analysis study.

Yuanzhi Xie1, Mina Mirzaei2, Mohammad Saeed Kahrizi3

  • 1Department of Reproductive Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.

Journal of Assisted Reproduction and Genetics
|June 18, 2022
PubMed
Summary
This summary is machine-generated.

COVID-19 (coronavirus disease 2019) infection negatively impacts male fertility by reducing sperm quality. This meta-analysis confirms SARS-CoV-2

Keywords:
COVID-19Male infertilityMale reproductionSARS-CoV-2 infectionSemen parameters

More Related Videos

Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
05:44

Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm

Published on: March 1, 2019

8.3K
Fish Sperm Assessment Using Software and Cooling Devices
07:57

Fish Sperm Assessment Using Software and Cooling Devices

Published on: July 28, 2018

8.9K

Related Experiment Videos

Last Updated: Sep 7, 2025

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
08:48

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects

Published on: April 21, 2022

2.7K
Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
05:44

Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm

Published on: March 1, 2019

8.3K
Fish Sperm Assessment Using Software and Cooling Devices
07:57

Fish Sperm Assessment Using Software and Cooling Devices

Published on: July 28, 2018

8.9K

Area of Science:

  • Reproductive Medicine
  • Virology
  • Public Health

Background:

  • The COVID-19 pandemic raised concerns about SARS-CoV-2 effects on male reproductive health.
  • Existing studies on SARS-CoV-2 impact on male fertility show inconsistent results.
  • The male reproductive system is considered vulnerable to SARS-CoV-2 infection.

Purpose of the Study:

  • To conduct a meta-analysis evaluating the impact of COVID-19 on male reproductive parameters.
  • To clarify the relationship between SARS-CoV-2 infection and male infertility.
  • To provide a comprehensive overview of current evidence on COVID-19's effects on male fertility.

Main Methods:

  • Systematic literature search across Embase, Web of Science, PubMed, and Google Scholar.
  • Inclusion of twelve studies (7 case-control, 5 retrospective cohort).
  • Statistical analysis using standardized mean difference (SMD) with 95% confidence intervals (CI), including heterogeneity, sensitivity, and publication bias testing.

Main Results:

  • SARS-CoV-2 infection was associated with significant reductions in semen volume, sperm concentration, sperm count, sperm motility, and progressive motility.
  • No significant association was found for sperm concentration and progressive motility in case-control studies.
  • No publication bias was detected in the meta-analysis.

Conclusions:

  • Semen quality is vulnerable to SARS-CoV-2 infection, with a significant negative association observed.
  • COVID-19 infection may temporarily impair male fertility potential.
  • Further research is necessary to determine the long-term effects of SARS-CoV-2 on male fertility.