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Updated: Sep 7, 2025

A Free-breathing fMRI Method to Study Human Olfactory Function
Published on: July 30, 2017
Assessment and Scientific Progresses in the Analysis of Olfactory Evoked Potentials
Pasquale Arpaia1, Andrea Cataldo2, Sabatina Criscuolo1
1Department of Information Technology and Electrical Engineering (DIETI), University of Naples Federico II, 80125 Napoli, Italy.
Abstract:
The human sense of smell is important for many vital functions, but with the current state of the art, there is a lack of objective and non-invasive methods for smell disorder diagnostics. In recent years, increasing attention is being paid to olfactory event-related potentials (OERPs) of the brain, as a viable tool for the objective assessment of olfactory dysfunctions. The aim of this review is to describe the main features of OERPs signals, the most widely used recording and processing techniques, and the scientific progress and relevance in the use of OERPs in many important application fields. In particular, the innovative role of OERPs is exploited in olfactory disorders that can influence emotions and personality or can be potential indicators of the onset or progression of neurological disorders. For all these reasons, this review presents and analyzes the latest scientific results and future challenges in the use of OERPs signals as an attractive solution for the objective monitoring technique of olfactory disorders.
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