Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AgNPs-Cellulose Nanofiber/Polyacrylamide Hydrogels as an Antibacterial Platform for Soft Tissue.

Gels (Basel, Switzerland)·2026
Same author

Covalent Immobilization of Crown Ether on Cellulose Acetate Membranes for Enhanced Heavy Metal Ion Retention.

Polymers·2026
Same author

Cellulose Acetate/Hydroxyapatite-Dexamethasone Loaded Membranes for the Prevention of Implant-Associated Acute Inflammation.

Polymers·2026
Same author

Study on the Influence of Hydroxyapatite on Human Cell Viability and Adhesion in Chemical Antibacterial Silver Coatings.

Dentistry journal·2026
Same author

Evaluation of Post-Processing Time's Influence on Biocompatibility of 3D-Printed Denture Base Resins.

Journal of functional biomaterials·2026
Same author

Correction: Cernencu et al. 3D Bioprinting of Biosynthetic Nanocellulose-Filled GelMA Inks Highly Reliable for Soft Tissue-Oriented Constructs. <i>Materials</i> 2021, <i>14</i>, 4891.

Materials (Basel, Switzerland)·2026

Related Experiment Video

Updated: Sep 6, 2025

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues
11:31

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues

Published on: August 28, 2014

13.5K

Nanostructured Polyacrylamide Hydrogels with Improved Mechanical Properties and Antimicrobial Behavior.

Elena Olăreț1, Ștefan Ioan Voicu1,2, Ruxandra Oprea2

  • 1Advanced Polymer Materials Group, University Politehnica of Bucharest, 011061 Bucharest, Romania.

Polymers
|June 24, 2022
PubMed
Summary

This study introduces nanostructured hydrogels reinforced with silver-decorated carbon nanotubes for cartilage repair. These materials exhibit enhanced mechanical strength and antibacterial properties, showing stability for tissue regeneration applications.

Keywords:
antibacterial activitymechanical propertiesnanostructured polyacrylamidesilver-decorated carbon nanotubes

More Related Videos

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.2K
Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.1K

Related Experiment Videos

Last Updated: Sep 6, 2025

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues
11:31

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues

Published on: August 28, 2014

13.5K
Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.2K
Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.1K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Nanotechnology

Background:

  • Articular cartilage defects require advanced regenerative strategies.
  • Hydrogels offer promising biocompatibility for tissue repair.
  • Enhancing mechanical properties and adding antimicrobial features are crucial for effective cartilage regeneration.

Purpose of the Study:

  • To develop nanostructured hydrogels with improved mechanical and antibacterial properties for articular cartilage regeneration.
  • To investigate the role of silver-decorated carbon nanotubes (Ag@CNTs) as reinforcing agents.
  • To assess the stability and suitability of the developed hydrogels for cartilage repair applications.

Main Methods:

  • Fabrication of semi-interpenetrating polymer networks using polyacrylamide (PAAm) and PAAm-methylene-bis-acrylamide (MBA).
  • Incorporation of low amounts of silver-decorated carbon nanotubes (Ag@CNTs) as reinforcing agents.
  • Mechanical testing (compression resilience, ultimate stress), stability tests (4-week incubation), and micro-computed tomography for morphometric analysis.

Main Results:

  • The nanostructured hydrogels demonstrated enhanced mechanical properties, including resilience and ultimate compression stress.
  • Ag@CNTs effectively reinforced the hydrogel network and imparted significant antibacterial characteristics.
  • The materials exhibited excellent stability with minimal degradation over 4 weeks and possessed adequate morphometric features for cartilage tissue engineering.

Conclusions:

  • The developed nanostructured hydrogels show significant potential for articular cartilage regeneration and repair due to their enhanced mechanical strength and antimicrobial activity.
  • The combination of a PAAm-MBA backbone, linear PAAm, and Ag@CNTs provides a robust and functional scaffold.
  • These findings support the use of Ag@CNT-reinforced hydrogels as advanced biomaterials for orthopedic applications.