Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

371
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
371
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

700
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
700

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spectrum of Dystonia in Spinocerebellar Ataxia.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same author

Why the Second-Hit Hypothesis Merits Center Stage in Peripherally Induced Movement Disorders?

Movement disorders : official journal of the Movement Disorder Society·2025
Same author

Clinical Reasoning: A 66-Year-Old Man With Chronic Orthostatic Hypotension.

Neurology·2025
Same author

Waveform-Based Analysis of Head Tremor Using a Marker-Less Tracking Algorithm with 2D-Video: Evaluation of Sinusoidality and Rhythmicity.

Movement disorders : official journal of the Movement Disorder Society·2025
Same author

Approach to Cardiovascular Autonomic Dysfunction in Patients with Synucleinopathies.

Movement disorders clinical practice·2025
Same author

Reply to: "Toward Refining and Unifying the Evaluation of Temporal Dimensions in Dystonia and Other Movement Disorders".

Movement disorders : official journal of the Movement Disorder Society·2025
Same journal

Efficacy and Safety of Perampanel in Patients With Brain Tumor-Related Epilepsy: A Systematic Review and Meta-Analysis.

Neurology. Clinical practice·2026
Same journal

Patient-Reported Symptom Burden in Individuals With Parkinson Disease.

Neurology. Clinical practice·2026
Same journal

Global Access to Diagnostic Paraclinical Testing Incorporated in the 2024 Revised McDonald Criteria: Disparities and Opportunity.

Neurology. Clinical practice·2026
Same journal

Clinical Differentiation of Self-Limited Epilepsy With Autonomic Seizures (Panayiotopoulos Syndrome) and Childhood Migraine.

Neurology. Clinical practice·2026
Same journal

The National Association of Epilepsy Centers Accreditation Criteria Should Include Care for People With Functional/Dissociative Seizures.

Neurology. Clinical practice·2026
Same journal

Long-Term Outcomes in Antibody-Negative Autoimmune Encephalitis: A Systematic Review and Meta-Analysis.

Neurology. Clinical practice·2026
See all related articles

Related Experiment Video

Updated: Sep 6, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.1K

Essential Tremor: Five New Things.

Abhishek Lenka1, Sanjay Pandey1

  • 1MedStar Georgetown University Hospital (AL), Washington, DC; and G.B. Pant Institute of Postgraduate Medical Education and Research (SP), New Delhi, India.

Neurology. Clinical Practice
|June 24, 2022
PubMed
Summary
This summary is machine-generated.

Essential tremor (ET) research advances include a new definition and "ET plus" category. Diagnosis and treatment, including cerebellar degeneration insights and MRgFUS thalamotomy, are evolving.

More Related Videos

An Instrumented Pull Test to Characterize Postural Responses
12:18

An Instrumented Pull Test to Characterize Postural Responses

Published on: April 6, 2019

10.9K
Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography
04:06

Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography

Published on: January 12, 2024

702

Related Experiment Videos

Last Updated: Sep 6, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.1K
An Instrumented Pull Test to Characterize Postural Responses
12:18

An Instrumented Pull Test to Characterize Postural Responses

Published on: April 6, 2019

10.9K
Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography
04:06

Author Spotlight: Enhancing Remote Rehabilitation with Virtual Reality and Electromyography

Published on: January 12, 2024

702

Area of Science:

  • Neurology
  • Neuroscience
  • Clinical Research

Background:

  • Essential tremor (ET) is a common neurological disorder.
  • Recent advancements necessitate updates in understanding and managing ET.

Purpose of the Study:

  • To review five key developments in essential tremor research and clinical practice.
  • To highlight a new definition, the "ET plus" category, diagnostic approaches, pathogenesis insights, and therapeutic innovations.

Main Methods:

  • Review of recent consensus statements and scientific literature.
  • Analysis of emerging evidence in ET pathogenesis and treatment.

Main Results:

  • A new definition and "ET plus" category have been proposed.
  • The cerebellar neurodegenerative model is favored over the olivary model for pathogenesis.
  • Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is a new therapeutic option.

Conclusions:

  • The understanding and clinical approach to essential tremor are significantly evolving.
  • New diagnostic criteria and therapeutic options offer improved management strategies for ET patients.