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Multi-electrode platform for selective electrochemical sensing: 3D-printed insulating plastic is turned into a
Daniel A Gonçalves1, Glinka L D Estadulho2, Katia-Emiko Guima2
1Faculty of Exact Sciences and Technology, Federal University of Grande Dourados, 79804-970, Dourados, MS, Brazil.
Talanta
|June 27, 2022
Summary
This study presents a novel method to create a multi-analyte sensing chip from 3D-printed plastic. The chip enables simultaneous detection of hydroquinone, acetaminophen, salicylic acid, and hydroxychloroquine using palladium, nickel, and ruthenium electrodes.
Area of Science:
- Electrochemistry
- Materials Science
- Analytical Chemistry
Background:
- Developing selective and cost-effective electrochemical sensors is crucial for multi-analyte detection.
- Traditional multi-analyte detection often requires complex instrumentation and multiple steps.
Purpose of the Study:
- To present a novel method for fabricating a multi-electrode electrochemical sensor chip from 3D-printed plastic.
- To demonstrate the simultaneous detection of four different analytes using the developed chip.
Main Methods:
- Utilizing 3D printing to create a plastic chip housing five electrodes, including palladium (Pd), nickel (Ni), and ruthenium (Ru).
- Employing sequential analysis by altering electrode connections without modifying mobile parts, reactants, or electrolytes.
Main Results:
- The fabricated chip successfully detected hydroquinone, acetaminophen, salicylic acid, and hydroxychloroquine simultaneously.
- The sequential analysis method proved effective for selective detection of multiple analytes.
Conclusions:
- The 3D-printed electrochemical sensor chip offers a low-cost and selective platform for simultaneous multi-analyte detection.
- This approach provides a simplified alternative to conventional methods for electrochemical sensing.

