Gold-catalysed rearrangement of unconventional cyclopropane-tethered 1,5-enynes
Rubén Vicente1, Eva Tudela1, Miguel A Rodríguez2
1Departamento de Química Orgánica e Inorgánica and Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo C/Julian Clavería 8, 33006, Oviedo, Spain. vicenteruben@uniovi.es.
Abstract:
The synthesis of particular cyclopropane-tethered 1,5-enynes, namely 6-alkynyl-4-alkylidenebicyclo[3.1.0]hex-2-enes, enabled the discovery of unprecedented gold-catalyzed rearrangment to indenes. A computational study of the mechanism of this profound skeleton rearrangement is also disclosed.
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