Management of the patient with cystinuria

Cystinuria is a complex hereditary disorder characterized by excessive urinary excretion of cystine. For the homozygote patient who excretes more than 400 mg per day, recurrent urinary calculus formation can necessitate repeat surgical manipulation with its associated morbidity. This review details the long-term medical management program for the patient with cystinuria and recurrent calculus formation.