Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Navigating the glycomics landscape with CE-MS: advances in sample preparation and analytical strategies.

The Analyst·2026
Same author

Longitudinal Maternal IgG and IgA Glycosylation Profiles in Pregnancy Reveal Early Immune Alterations in Placenta-Related Complications: The Rotterdam Periconception Cohort.

Hypertension (Dallas, Tex. : 1979)·2026
Same author

Fc-fucosylation of Plasmodium falciparum-specific IgG varies with antigen and immunization.

The Journal of infectious diseases·2026
Same author

Validation approach of an LC-MS/MS assay for ADA detection, applied to a Von Willebrand factor-targeted biotherapeutic.

Bioanalysis·2026
Same author

Large glycomics datasets as a tool to understand the function of glycans.

Nature chemical biology·2026
Same author

Determinants of Immunoglobulin-G N-Glycan Patterns in the Aging General Population.

Allergy·2026

Related Experiment Video

Updated: Sep 5, 2025

A Quantitative Glycomics and Proteomics Combined Purification Strategy
11:38

A Quantitative Glycomics and Proteomics Combined Purification Strategy

Published on: March 8, 2016

15.1K

High-Throughput Glycomic Methods.

Irena Trbojević-Akmačić1, Guinevere S M Lageveen-Kammeijer2, Bram Heijs2

  • 1Genos, Glycoscience Research Laboratory, Borongajska cesta 83H, 10 000 Zagreb, Croatia.

Chemical Reviews
|July 7, 2022
PubMed
Summary

Glycomics studies the complete set of sugars (glycans) in cells. High-throughput glycomics uses advanced technologies for rapid analysis of glycomes, crucial for understanding health and disease.

More Related Videos

Author Spotlight: MAPP Protocol – Advancing Glycan Analysis
07:12

Author Spotlight: MAPP Protocol – Advancing Glycan Analysis

Published on: September 29, 2023

1.9K
Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
13:21

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples

Published on: May 4, 2012

15.8K

Related Experiment Videos

Last Updated: Sep 5, 2025

A Quantitative Glycomics and Proteomics Combined Purification Strategy
11:38

A Quantitative Glycomics and Proteomics Combined Purification Strategy

Published on: March 8, 2016

15.1K
Author Spotlight: MAPP Protocol – Advancing Glycan Analysis
07:12

Author Spotlight: MAPP Protocol – Advancing Glycan Analysis

Published on: September 29, 2023

1.9K
Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
13:21

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples

Published on: May 4, 2012

15.8K

Area of Science:

  • Glycomics and glycobiology
  • Analytical chemistry
  • Biotechnology

Background:

  • Glycomics aims to elucidate the structure and function of the glycome.
  • Glycosylation is a complex biological process influenced by genes and other factors.
  • High-throughput glycomics requires robust, sensitive, and automatable analytical technologies.

Purpose of the Study:

  • To provide a historic overview of glycomic profiling.
  • To highlight recent developments and challenges in high-throughput glycomics.
  • To focus on N-glycosylation analysis as a key area.

Main Methods:

  • Review of prominent high-throughput glycomic approaches.
  • Description of current state-of-the-art characterization levels.
  • Discussion of widely used analytical technologies.

Main Results:

  • Overview of historical advancements in glycomics.
  • Summary of recent technological developments in high-throughput analysis.
  • Identification of key challenges in glycomic profiling.

Conclusions:

  • High-throughput glycomics is essential for timely analysis of numerous glycomes.
  • N-glycosylation analysis is a focal point for current glycomic research.
  • Applications span deciphering glycosylation in health and disease states.