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A Review: Current Status and Emerging Developments on Natural Polymer-Based Electrospun Fibers.

Weisen Han1, Liangyu Wang1, Qin Li1

  • 1Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, P. R. China.

Macromolecular Rapid Communications
|July 17, 2022
PubMed
Summary

Natural polymer electrospun fibers (EFs) offer significant advantages for biomedical applications due to their large surface area and biocompatibility. This review details electrospinning parameters, raw materials, fiber structures, and their use in tissue engineering, drug delivery, and sensors.

Keywords:
biomedical applicationelectrospun fiberspolysaccharidesproteins

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Biomedical Engineering

Background:

  • Natural polymer-based electrospun fibers (EFs) are gaining prominence in biomedical fields.
  • Their properties include large specific surface area, biocompatibility, and biological activity.
  • Electrospinning is a key technique for fabricating these advanced materials.

Purpose of the Study:

  • To provide a comprehensive overview of natural polymer-based EFs.
  • To detail the parameters influencing electrospinning and material characteristics.
  • To summarize the diverse biomedical applications of these EFs.

Main Methods:

  • Detailed review of electrospinning parameters (solution and process).
  • Summarization of natural polymer raw materials (polysaccharides and proteins).
  • Introduction to various EFs structures (porous, core-shell, etc.).

Main Results:

  • Electrospinning parameters significantly impact fiber morphology and properties.
  • A wide range of natural polymers can be utilized for EFs fabrication.
  • Multistage structures enhance functional characteristics for specific applications.

Conclusions:

  • Natural polymer-based EFs are versatile materials for advanced biomedical applications.
  • Further research into electrospinning optimization and novel applications is warranted.
  • These EFs hold great promise for tissue engineering, drug delivery, wound dressings, and sensors.