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Updated: Sep 4, 2025

Intracranial Injection of Adeno-associated Viral Vectors
Published on: November 17, 2010
ANCA-Associated Vasculitis following the First Dose of Pfizer-BioNTech COVID-19 Vaccine
Georges El Hasbani1, Imad Uthman2
1Department of Internal Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut, USA, george.hasbany@lau.edu.
Abstract:
Coronavirus disease (COVID-19) vaccine can alter the body's immunological balance leading to autoimmune disease in rare cases. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is one of the autoimmune diseases which have been rarely reported to appear post-COVID-19 vaccine. Herein, we report the case of a 47-year-old woman who developed acute renal failure few days after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine. Corticosteroids along with azathioprine were used for the management.
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