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Published on: September 27, 2024
The Cardiovascular Manifestations of COVID-19
David W Louis1, Marwan Saad1, Shilpa Vijayakumar1
1Lifespan Cardiovascular Institute, 593 Eddy Street, RIH APC 730, Providence, RI 02903, USA; Department of Medicine, Division of Cardiology, Alpert Medical School of Brown University, 222 Richmond Street, Providence, RI 02903, USA.
Insights
The COVID-19 pandemic, caused by SARS-CoV-2, is linked to severe cardiovascular issues like heart failure and thrombosis, impacting patient outcomes. This review examines COVID-19
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic has caused significant global morbidity and mortality.
- Beyond respiratory illness, COVID-19 frequently manifests with serious cardiovascular complications.
Purpose of the Study:
- To review the intricate relationship between cardiovascular risk factors and COVID-19 outcomes.
- To detail the diverse cardiovascular manifestations observed in COVID-19 patients.
- To explore cardiovascular complications linked to COVID-19 vaccination.
Main Methods:
- Literature review of studies on COVID-19 and cardiovascular health.
- Analysis of reported cardiovascular manifestations and complications.
- Examination of data on COVID-19 vaccination and cardiovascular events.
Main Results:
- COVID-19 is associated with increased risks of acute coronary syndromes, thrombosis, heart failure, and arrhythmias.
- These cardiovascular complications correlate with adverse patient outcomes, including mortality.
- Cardiovascular risk factors significantly influence COVID-19 prognosis.
Conclusions:
- Understanding the cardiovascular impact of COVID-19 is critical for patient management.
- Further research is needed to elucidate the mechanisms behind COVID-19's cardiovascular effects and vaccination-related complications.
Abstract:
The Coronavirus 2019 (COVID-19) pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) virus, has resulted in unprecedented morbidity and mortality worldwide. While COVID-19 typically presents as viral pneumonia, cardiovascular manifestations such as acute coronary syndromes, arterial and venous thrombosis, acutely decompensated heart failure (HF), and arrhythmia are frequently observed. Many of these complications are associated with poorer outcomes, including death. Herein we review the relationship between cardiovascular risk factors and outcomes among patients with COVID-19, cardiovascular manifestations of COVID-19, and cardiovascular complications associated with COVID-19 vaccination.
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