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Updated: Sep 4, 2025

Lateral Chronic Cranial Window Preparation Enables In Vivo Observation Following Distal Middle Cerebral Artery Occlusion in Mice
Published on: December 29, 2016
[COVID-19-Induced Cerebrovascular Disease]
Takeshi Yoshimoto1, Kazunori Toyoda
1Department of Neurology, National Cerebral and Cardiovascular Center.
COVID-19 can cause neurological issues like ischemic stroke due to a pro-thrombotic state. While stroke risk is elevated, COVID-19-induced ischemic stroke cases decreased in 2022 compared to earlier pandemic phases.
Area of Science:
- Neurology
- Infectious Diseases
- Cardiovascular Medicine
Background:
- COVID-19 is associated with an increasing number of neurological complications.
- The virus can induce a pro-thrombotic state, elevating the risk of ischemic stroke.
- Clinical observations indicate a potential shift in the incidence of COVID-19-related strokes.
Purpose of the Study:
- To describe the association between COVID-19 and stroke.
- To review the pathophysiology and prognosis of stroke in COVID-19 patients.
- To present the latest literature on this topic.
Main Methods:
- Literature review of COVID-19 and stroke.
- Analysis of clinical observations regarding neurological complications.
- Examination of pathophysiological mechanisms linking COVID-19 to thrombosis and stroke.
Main Results:
- COVID-19 is linked to a pro-thrombotic state, increasing ischemic stroke risk.
- The incidence of COVID-19-induced ischemic stroke was lower in 2022 than in the early pandemic.
- Neurological complications are a significant concern in COVID-19 patients.
Conclusions:
- Understanding the link between COVID-19 and stroke is crucial for patient management.
- The evolving incidence of COVID-19-related stroke warrants continued research.
- Further investigation into pathophysiology and prognosis is needed.
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