Screening for Individuals at Risk for Hereditary Breast and Ovarian Cancer: A Statewide Initiative, Georgia,
Julia K Veitinger1, Alice S Kerber1, Sheryl G A Gabram-Mendola1
1Julia K. Veitinger is with the Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA. Alice S. Kerber, Sheryl G. A. Gabram-Mendola, Lynn M. Durham, and Cindy Snyder are with the Georgia Center for Oncology Research and Education, Atlanta. Yuan Liu is with the Department of Biostatistics and Bioinformatics, Rollins School of Public Health & Winship Cancer Institute, Emory University. Diane Durrence, Alissa K. Berzen, and Janet Y. Shin are with the Georgia Department of Public Health, Atlanta. Cecelia A. Bellcross is with the Department of Human Genetics, Emory University School of Medicine, Atlanta. Yue Guan is with Department of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University.
Abstract:
Georgia implemented a statewide family history screening program for hereditary breast and ovarian cancer. From November 2012 through December 2020, 29 090 individuals were screened, 16 679 of whom (57.3%) self-identified as a racial/ethnic minority. Of the 4% (1172/29 090) of individuals who screened as high risk, more than half underwent genetic consultation (793/1172; 67.7%) and testing (416/589; 70.6%). Compared with White women, Black and Hispanic women had higher uptake rates of genetic consultation. Public health settings serving racial minorities are well suited to address disparities in genetic service access. (Am J Public Health. 2022;112(9):1249-1252. https://doi.org/10.2105/AJPH.2022.306932).
More Related Videos
13:04In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose
Published on: October 14, 2015
10:27Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
Published on: July 25, 2020
Related Concept Videos
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer Survival Analysis
Oogenesis
Preventive Healthcare Services
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
