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In vitro renal calculi destruction by a high-frequency glow discharge plasma
Sergej V Belov1, Yury K Danileyko1, Roman Y Pishchalnikov2
1Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia.
Scientific Reports
|July 25, 2022
Summary
High-frequency electrolyte plasma effectively destroys kidney stones in vitro through hydrated electron and shock wave effects. This promising method could advance endoscopic urology for renal calculi treatment.
Area of Science:
- Urology
- Plasma Physics
- Biomedical Engineering
Background:
- Current nephrolithiasis treatments have limitations.
- Renal calculi destruction methods present advantages and disadvantages.
Purpose of the Study:
- To investigate the efficacy of high-frequency glow discharge plasma for in vitro renal calculi destruction.
- To explore the mechanisms behind plasma-induced kidney stone fragmentation.
Main Methods:
- Utilizing high-frequency glow discharge plasma generated on an electrode-electrolyte surface.
- Configuring plasma generation by controlling vapor-gas layer thickness.
- Measuring the average rate of renal calculi destruction based on plasma input power and exposure time.
Main Results:
- Glow discharge plasma effectively fragments kidney stones in vitro.
- Destruction mechanisms include hydrated electron effects and electrolyte shock waves from plasma breakdowns.
- The rate of stone destruction correlates with plasma power and exposure duration.
Conclusions:
- High-frequency electrolyte plasma is a promising method for renal calculi fragmentation.
- This technique has potential applications in endoscopic urology, including percutaneous and transurethral lithotripsy.
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