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Updated: Sep 3, 2025

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Structural Revision of Parvistemoamide: Informing Biosynthetic Proposals of Stemona Alkaloids
Wesley J Olivier1, Jason A Smith1, Alex C Bissember1
1School of Natural Sciences (Chemistry), University of Tasmania, Hobart, Tasmania 7001, Australia.
Abstract:
The natural product parvistemoamide was isolated in 1991 and has ostensibly eluded synthesis. Its distinctive assigned structure represents the first and only Stemona alkaloid within its class. For over 30 years, this structure has influenced biosynthetic proposals concerning this family of natural products. Following synthetic studies and comprehensive analysis of relevant literature, a revised structure of parvistemoamide is proposed that is consistent with the fundamental Stemona alkaloid stemoamide.
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