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Updated: Sep 2, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Pre-eclampsia in a Sub-Saharan African country and maternal-perinatal outcome
Elie Nkwabong1, Franck Djientcheu Deugoue2, Jeanne Fouedjio3
1Department of Obstetrics and Gynecology; 260103Faculty of Medicine and Biomedical Sciences & University Teaching Hospital, University of Yaoundé I, Yaoundé, Cameroon.
Abstract:
Our comparative cohort study, carried out between 3rd January and 30th April 2020, looked at the maternal and perinatal outcomes associated with pre-eclampsia. Of 2019 booked pregnant women, 141 (7.0%) had pre-eclampsia, and 59.8% of these were severe at admission. Significant adverse maternal outcomes were eclampsia, HELLP (haemolysis, elevated liver enzymes, and low platelets) syndrome, and placental abruption, and significant adverse perinatal outcomes were intra-uterine fetal death, preterm delivery, low birth weight (LBW), neonatal asphyxia and early neonatal death. Close attention needs to be given to women with pre-eclampsia in poor resource circumstances.
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