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Related Concept Videos

Theories of Dissolution: Diffusion Layer Model01:15

Theories of Dissolution: Diffusion Layer Model

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Dissolution, the process by which drug particles dissolve in a solvent, is explained by the diffusion layer model, a theoretical framework that simulates the absorption of oral drugs and allows us to analyze experimental data.
This process starts with a thin layer, saturated with the drug, forming at the interface between the solid and liquid. The solute then diffuses from this layer into the main solution. The Noyes-Whitney equation suggests that the rate of dissolution relies on the diffusion...
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Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model01:09

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Various dissolution theories provide insight into the factors that influence the dissolution rate. Danckwerts' Model suggests that turbulence, rather than a stagnant layer, characterizes the dissolution medium at the solid-liquid interface. In this model, the agitated solvent contains macroscopic packets that move to the interface via eddy currents, facilitating the absorption and delivery of the drug to the bulk solution. The regular replenishment of solvent packets maintains the...
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Related Experiment Video

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Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
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Probing multiscale dissolution dynamics in natural rocks through microfluidics and compositional analysis.

Bowen Ling1, Mo Sodwatana1, Arjun Kohli1

  • 1Energy Resources Engineering, Stanford University, Stanford, CA 94305.

Proceedings of the National Academy of Sciences of the United States of America
|August 3, 2022
PubMed
Summary
This summary is machine-generated.

This study visualizes mineral dissolution in rocks using high-resolution, time-resolved imaging. It reveals how mineral distribution and fluid flow dynamics impact geological processes and subsurface engineering.

Keywords:
dissolutiongeochemistrymicrofluidicsmineralogy

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Area of Science:

  • Geochemistry
  • Geology
  • Material Science

Background:

  • Mineral dissolution is crucial in geological systems, influencing processes like carbon sequestration and acid injection.
  • Coupled geochemical reactions, fluid flow, and solute transport are complex, operating across vast timescales.
  • Existing experimental methods lack the resolution to observe dissolution in heterogeneous, intact rock samples.

Purpose of the Study:

  • To develop and apply a novel microfluidic platform for visualizing mineral dissolution in real-time.
  • To investigate the spatiotemporal dynamics of dissolution in shale samples with varying carbonate content.
  • To understand the impact of mineral heterogeneity on rock strength and fracture evolution.

Main Methods:

  • Utilized microfluidic cells with thin rock samples for high temporal (100 ms) and spatial resolution imaging.
  • Injected acidic fluid into eight shale samples (8-86 wt % carbonate).
  • Characterized pre- and post-reaction microstructures at pore and fracture scales.

Main Results:

  • Observed real-time dissolution dynamics, including two-phase flow effects.
  • Demonstrated that nonreactive particle exposure, fracture morphology, and rock strength depend on reactive grain volume and distribution.
  • Documented changes in the fracture interface across different sample compositions.

Conclusions:

  • The developed platform enables real-time characterization of geochemical reactions in heterogeneous media.
  • Findings provide insights into mineral dissolution dynamics relevant to subsurface engineering.
  • The study offers a method to characterize reactivity parameters in natural samples where porous media effects are significant.