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Related Concept Videos

Inhaled Medications01:23

Inhaled Medications

371
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
371
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

566
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
566
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

457
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
457

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Related Experiment Video

Updated: Sep 2, 2025

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
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Nanoparticle-Based Inhalation Therapy for Pulmonary Diseases.

Dhananjay Yadav1, Peninah M Wairagu2, Minseok Kwak3

  • 1Department of Life Science, Yeungnam University, Gyeongsan 38541, South Korea.

Current Drug Metabolism
|August 5, 2022
PubMed
Summary

Nanoparticles (NPs) offer a promising approach for treating lung diseases by enabling direct drug delivery. Their unique properties enhance therapeutic efficacy for pulmonary conditions like infections, allergies, and cancers.

Keywords:
Natural polymerbiomedical applicationslung therapynanoparticlephagocytosisrespiratory disease

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Area of Science:

  • Pulmonary Medicine
  • Nanotechnology
  • Pharmacology

Background:

  • The lung is susceptible to pollutants and diseases such as infections, allergies, and cancers.
  • Direct drug administration to the lung is a strategy to maintain topical drug concentrations.
  • Nanoscale particles can effectively reach the pulmonary region.

Purpose of the Study:

  • To describe the biological and pharmacological activities of nanoparticles (NPs).
  • To summarize the potential of NPs in formulating drugs for pulmonary diseases.
  • To highlight recent advances in NP-based inhalation chemotherapy for lung diseases.

Main Methods:

  • Review of biological and pharmacological activities of NPs.
  • Analysis of NP applications in drug formulation for lung diseases.
  • Examination of recent advancements in NP-based inhalation chemotherapy.

Main Results:

  • Nanoparticles exhibit unique physicochemical properties and biological activities.
  • NPs show significant potential in developing effective treatments for pulmonary diseases.
  • Inhalation chemotherapy using NPs is an emerging and promising treatment modality.

Conclusions:

  • Nanoparticles are valuable tools for targeted drug delivery to the lungs.
  • NPs can be effectively utilized in pharmaceutical formulations for treating lung diseases.
  • The application of NPs in inhalation chemotherapy represents a significant advancement in managing pulmonary conditions.