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Updated: Sep 2, 2025

Organotypic Tissue Model Systems for Investigating Host-Pathogen Interactions In Vitro
Published on: March 28, 2025
Mathematical modeling of intercellular interactions within the biofilm
Ao Xia1, Huize Chen1, Yun Huang1
1Key Laboratory of Low-grade Energy Utilization Technologies and Systems, Chongqing University, Ministry of Education, Chongqing 400044, PR China; Institute of Engineering Thermophysics, School of Energy and Power Engineering, Chongqing University, Chongqing 400044, PR China.
Abstract:
Bacteria accumulate and are embedded in a self-produced matrix, forming the biofilm. The interactions among cells drive the development of biofilms and provide properties that differ from planktonic cells. This forum article focuses on how intercellular mechanical interactions and physiological behaviors lead to community-scale features via exploring the applicability of biofilm mathematical models.

