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Semi-supervised vision transformer with adaptive token sampling for breast cancer classification.

Wei Wang1, Ran Jiang2, Ning Cui3

  • 1Department of Breast Surgery, Hubei Provincial Clinical Research Center for Breast Cancer, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Frontiers in Pharmacology
|August 8, 2022
PubMed
Summary

This study introduces a novel semi-supervised learning framework using Vision Transformers (ViT) for breast cancer (BC) detection. The ViT-based method enhances diagnostic accuracy, outperforming traditional convolutional neural network (CNN) models.

Keywords:
adaptive token samplingbreast cancer detectiondata enhancementsemi-supervised learningvision transformer

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Oncology

Background:

  • Machine learning (ML) and deep learning, particularly convolutional neural networks (CNNs), have advanced computer-aided diagnosis (CAD) for breast cancer (BC) detection and classification.
  • Supervised learning approaches have dominated ML-based BC detection, achieving expert-level accuracy.

Purpose of the Study:

  • To propose a novel semi-supervised learning framework for breast cancer detection utilizing the Vision Transformer (ViT) model.
  • To enhance the robustness and performance of BC detection models by integrating supervised and consistency training.
  • To explore the efficacy of ViT, a model less commonly applied to BC detection, in improving diagnostic accuracy.

Main Methods:

  • Development of a custom semi-supervised learning framework based on the Vision Transformer (ViT).
  • Implementation of a unified training procedure combining supervised learning and consistency training for enhanced model robustness.
  • Integration of an adaptive token sampling technique to focus on the most significant image features.

Main Results:

  • The proposed ViT-based semi-supervised framework demonstrated consistent performance improvements over CNN baselines.
  • Validation on both ultrasound and histopathology image datasets confirmed the method's effectiveness in breast cancer detection.
  • The adaptive token sampling technique contributed to significant performance gains.

Conclusions:

  • The Vision Transformer (ViT) shows significant promise for breast cancer detection, offering superior performance compared to traditional CNN models.
  • Semi-supervised learning, combined with adaptive token sampling, provides a robust and effective approach for improving BC diagnostic accuracy.
  • The developed framework offers a valuable advancement in AI-driven breast cancer diagnosis.