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Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
Yan Sun1, Rashmi Supriya1,2, Yang Gao1,2
1Department of Sport, Physical Education and Health, Hong Kong Baptist University, Hong Kong 999077, China.
Insights
Hypertension is prevalent in Chinese children with intellectual disability, affecting 31.4%. Obesity is the primary risk factor, highlighting the need for obesity prevention strategies in this population.
Area of Science:
- Pediatrics
- Public Health
- Cardiology
Background:
- Intellectual disability (ID) is associated with various health challenges.
- Hypertension (high blood pressure) prevalence and risk factors in children with ID are not well-understood, particularly in Chinese populations.
Purpose of the Study:
- To determine the prevalence of hypertension among Chinese children with intellectual disability.
- To identify associated risk factors for hypertension in this specific pediatric group.
Main Methods:
- A cross-sectional study involving 452 children (aged 6-18) with intellectual disability in Hong Kong.
- Blood pressure measurement using standard protocols and 2018 Chinese Guidelines for Children criteria.
- Multivariate and hierarchical logistic regression analyses to identify risk factors.
Main Results:
- The prevalence of hypertension was 31.4% in the studied population.
- Obesity was significantly associated with a higher risk of hypertension (adjusted OR = 2.77).
- Paternal education (college or above) and paternal occupation (clerks, sales representatives, workers) were also linked to increased hypertension risk.
Conclusions:
- Hypertension is highly prevalent in Chinese children with intellectual disability.
- Obesity is the strongest identified risk factor, suggesting targeted prevention is crucial.
- Preventing obesity may offer dual benefits for both obesity and hypertension management in children with ID.
Abstract:
To investigate the prevalence of hypertension and associated risk factors in Chinese children with intellectual disability, a cross-sectional study was conducted in a sample of 558 children with intellectual disability aged 6-18 years in Hong Kong, and 452 (81.0%) with valid data were included in the data analysis. Blood pressure was measured according to a standard protocol. Hypertension was defined using the age-, gender-, and height-specific classification criteria recommended by the 2018 Chinese Guidelines for Children. Multivariate and hierarchical logistic regression was fitted to examine the associations of hypertension with potential risk factors. Overall, 31.4% of the participants were classified as having hypertension. Obese children were more likely to develop hypertension than non-obese children (adjusted OR = 2.77, 95% CI: 1.28, 5.99, p = 0.010). A paternal education of college or above and a paternal occupation of clerks, sales representatives, and workers were also associated with an increased risk of hypertension. The prevalence of hypertension is high among Chinese children with intellectual disability. Obesity was the strongest risk factor. Further longitudinal studies are warranted to confirm our findings. Nevertheless, preventions against obesity are promising to receive doubled benefits in reducing both obesity and hypertension, given its strong relationship with hypertension in this special population.
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