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Complications by liquid plastics in ophthalmic surgery. Histopathologic study
Developments in Ophthalmology
|January 1, 1987
Summary
Liquid plastics used in ophthalmology can cause serious complications, including lacrimal sac obstruction and corneal cell loss. Further research is needed for safer materials in eye treatments.
Area of Science:
- Ophthalmology
- Biomaterials Science
- Histopathology
Background:
- Ocular treatments increasingly utilize liquid plastics and biomaterials.
- Understanding the long-term effects of these materials on ocular tissues is crucial.
Observation:
- Retrospective studies analyzed ocular tissues treated with liquid plastics.
- Complications observed include dacryocystitis, xanthogranuloma, and significant cell loss in the cornea.
Findings:
- Cyanoacrylates for punctal occlusion can migrate, causing lacrimal sac obstruction and inflammation.
- Use of cyanoacrylates with hard contact lenses leads to corneal stromal and endothelial cell loss.
- Intraocular silicone oil can induce epiretinal macrophage activity and fibrosis if it enters the subretinal space.
Implications:
- Current liquid alloplasts for intraocular lens surgery are not yet satisfactory.
- These findings highlight the need for improved biomaterial safety and efficacy in ophthalmic applications.
- Further development is required to mitigate risks associated with liquid plastics in ocular procedures.