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Updated: Sep 1, 2025

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Published on: May 1, 2021
[Focus on the diagnosis and treatment of blepharokeratoconjunctivitis in children]
1Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China.
Insights
Pediatric blepharokeratoconjunctivitis (BKC) is a common, yet poorly understood, chronic eye inflammation in children. This review highlights the need for standardized diagnosis and treatment to prevent vision impairment.
Area of Science:
- Ophthalmology
- Pediatric Eye Diseases
Background:
- Blepharokeratoconjunctivitis (BKC) is a prevalent chronic inflammatory ocular surface disease in children.
- Current understanding of pediatric BKC etiology and clinical characteristics remains limited, with a lack of expert consensus in China.
- Atypical presentations in children often lead to diagnostic and therapeutic challenges.
Purpose of the Study:
- To review the current status of etiology, diagnosis, and treatment of pediatric BKC.
- To discuss the clinical characteristics of BKC in children.
- To advocate for standardized diagnostic and therapeutic approaches for pediatric BKC.
Main Methods:
- Literature review of pediatric blepharokeratoconjunctivitis.
- Analysis of current diagnostic and treatment strategies.
- Comparison of clinical manifestations in pediatric versus adult patients.
Main Results:
- The etiology of pediatric BKC is not well-established.
- Clinical manifestations in children are often atypical compared to adults.
- Inadequate diagnosis and treatment are prevalent due to a lack of understanding and standardized guidelines.
Conclusions:
- There is an urgent need for increased attention to pediatric BKC among ophthalmologists.
- Standardized diagnostic criteria and treatment protocols are essential for effective management.
- Further research is required to elucidate the etiology and improve outcomes for children with BKC.
Abstract:
Blepharokeratoconjunctivitis, (BKC) is a common ocular surface chronic inflammatory disease in children. It can cause eye irritation or even visual impairment. At present, the etiology of BKC in children is not clear and relevant studies are in the initial stage, consequently, there has not been an authoritative applicable expert consensus in China. Compared with adults, the clinical manifestations of pediatric patients are often atypical, coupled with the lack of understanding, so inadequate diagnosis and treatment are still exist in pediatric BKC. This article reviews the etiology, diagnosis and treatment status, clinical characteristics, standardized diagnosis and treatment of pediatric BKC, in order to arouse the attention of ophthalmologists.
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