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Updated: Aug 31, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
Prophylactic antibiotics may not be necessary for transoral endoscopic thyroidectomy
Jun Sung Lee1, Hee Jun Kim2, Jin Seok Lee1
1Department of Surgery, Thyroid Cancer Center, Gangnam Severance Hospital, Institute of Refractory Thyroid Cancer, Yonsei University College of Medicine, Seoul, South Korea.
Transoral endoscopic thyroidectomy (TOET) is not a clean-contaminated surgery, as bacterial cultures showed no significant changes and no infections occurred. This minimally invasive thyroid cancer surgery is safe and effective, with minimal risk of bacterial contamination.
Area of Science:
- Endocrine Surgery
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Transoral endoscopic thyroidectomy (TOET) is gaining popularity globally due to advances in surgical techniques and patient cosmetic concerns.
- The classification of TOET as a clean-contaminated surgery requires further investigation.
Purpose of the Study:
- To determine if transoral endoscopic thyroidectomy (TOET) qualifies as a clean-contaminated surgical procedure.
- To assess the risk of bacterial contamination and surgical site infections associated with TOET.
Main Methods:
- A prospective study involving 20 patients undergoing TOET for thyroid cancer between September 2016 and April 2018.
- Oral cavity cultures were obtained preoperatively and postoperatively.
- Patients received prophylactic antibiotics before and after surgery.
Main Results:
- No surgical site infections were observed in any of the 20 patients.
- Bacterial presence in oral cultures showed no significant difference between pre- and postoperative samples.
- All identified bacteria were normal oral or skin flora, indicating no pathogenic invasion.
Conclusions:
- Transoral endoscopic thyroidectomy (TOET) does not appear to be a clean-contaminated surgery based on bacterial culture results.
- Prophylactic antibiotic use and the surgical approach likely minimize the risk of bacterial contamination and infection.
- The anatomical position and surgical extent in TOET create a barrier against non-indigenous bacterial invasion.
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