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Updated: Aug 31, 2025

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research
Published on: July 31, 2017
Comorbidities in Children with Autism Spectrum Disorder Undergoing Oral Rehabilitation Under General Anesthesia
Nathan Blair1, Jennifer Feingold2, Fang Qian3
1Dr. Blair is a clinical assistant professor, Division of Pediatric Anesthesia, Department of Anesthesiology, University of Iowa Hospitals and Clinics, University of Iowa, Iowa City, Iowa, USA;,
Abstract:
Purpose:To investigate the oral health needs and comorbidities among patients with autism spectrum disorder (ASD) undergoing oral rehabilitation under general anesthesia (GA) at a university hospital.
Methods: Records of patients with ASD who underwent oral rehabilitation under GA between January 2016 and May 2019 were reviewed to identify comorbid conditions and oral health needs. Statistical analysis consisted of descriptive and bivariate analyses (alpha = 0.05).
Results:A total of 160 patients from three to 18 years of age fulfilled the inclusion criteria. Seventy-eight percent were male and 69 percent had public insurance. Be- havioral issues, such as anxiety, aggression and nonverbal status, were observed more frequently than reported in the ASD literature. Dental caries, poor oral hygiene and gingivitis were the most common dental conditions observed. Radiographs, sealants, stainless steel crowns and extractions were the most common treatments rendered. Bivariate analysis revealed that subjects who had eight to 15 comorbidities were likely to be older.
Conclusions: Patients with ASD have many dental needs and may have comorbid medical conditions that directly affect the safe delivery of GA and dental treatments. As patients with ASD age, the number of comorbidities increases.
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