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Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
Published on: October 25, 2024
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COVID-19 vaccination, implications for PET/CT image interpretation and future perspectives.
Margarita Kirienko1, Matteo Biroli2, Cristiano Pini2,3
1Fondazione IRCCS Istituto Nazionale Tumori, Via G. Venezian 1, 20133 Milan, Italy.
Clinical and Translational Imaging
|August 22, 2022
Summary
COVID-19 vaccination can cause temporary changes on PET/CT scans, such as increased uptake in the deltoid muscle and lymph nodes. Awareness of these vaccine-related findings is crucial for accurate interpretation.
Area of Science:
- Radiology
- Nuclear Medicine
- Immunology
Background:
- Positron Emission Tomography/Computed Tomography (PET/CT) is a key imaging modality.
- Understanding imaging findings related to COVID-19 vaccination is essential for accurate diagnosis.
Purpose of the Study:
- To systematically review literature on COVID-19 vaccine-related findings in patients undergoing PET/CT.
- To identify common PET/CT findings associated with COVID-19 vaccination.
Main Methods:
- Systematic literature review using search terms related to PET/CT, COVID-19, and vaccination.
- Inclusion of 17 articles assessed for quality.
Main Results:
- The most frequent vaccine-related findings on PET/CT were deltoid [18F]FDG uptake (8-71%) and axillary hypermetabolic lymph nodes (7-90%).
- Variability in findings was noted with different tracers, time since vaccination, and positivity criteria.
- Findings were more common in younger, immunocompetent individuals.
Conclusions:
- Awareness of vaccination status, including timing and patient characteristics, is necessary for proper interpretation of PET/CT findings.
- Knowledge of radiopharmaceutical uptake patterns related to COVID-19 vaccination aids accurate interpretation.
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