Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bioactive IGF-I Concentrations in Children on GH Therapy.

The Journal of clinical endocrinology and metabolism·2025

Same author

Effects of Puberty Suppression and Sex Steroids on Weight, BMI, and Lipid Profiles in Danish Transgender Adolescents.

The Journal of clinical endocrinology and metabolism·2025

Same author

QCD challenges from pp to AA collisions: 4th edition.

The European physical journal. C, Particles and fields·2024

Same author

Growth and Adult Height Attainment in Danish Transgender Adolescents Treated With GnRH Analog and Sex Hormones.

The Journal of clinical endocrinology and metabolism·2024

Same author

Differentiation of Idiopathic Central Precocious Puberty From Premature Thelarche Using Principal Component Analysis.

The Journal of clinical endocrinology and metabolism·2023

Same author

Reduced serum concentrations of biomarkers reflecting Leydig and Sertoli cell function in male patients with congenital adrenal hyperplasia.

Endocrine connections·2023

Search research articles

Related Experiment Video

Updated: Aug 31, 2025

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

Varian eclipse stereotactic 5 mm cone data commissioning.

Dominika Firth¹, Penny Fogg², Peter Christiansen²

¹GenesisCare, Buderim, QLD, Australia. Dominika.firth@genesiscare.com.

Physical and Engineering Sciences in Medicine

|August 23, 2022

Summary

Commissioning stereotactic radiosurgery fields requires accurate data. This study successfully commissioned a Varian 5 mm cone, validating measurements against established data and ensuring precise dose calculations for advanced cancer treatments.

Keywords:

Conical collimator Gamma analysis Microdiamond SRS diode Stereotactic radiosurgery Varian TrueBeam

More Related Videos

Operative Technique and Nuances for the Stereoelectroencephalographic SEEG Methodology Utilizing a Robotic Stereotactic Guidance System

Operative Technique and Nuances for the Stereoelectroencephalographic SEEG Methodology Utilizing a Robotic Stereotactic Guidance System

Published on: June 9, 2023

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Related Experiment Videos

Last Updated: Aug 31, 2025

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

Operative Technique and Nuances for the Stereoelectroencephalographic SEEG Methodology Utilizing a Robotic Stereotactic Guidance System

Operative Technique and Nuances for the Stereoelectroencephalographic SEEG Methodology Utilizing a Robotic Stereotactic Guidance System

Published on: June 9, 2023

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Area of Science:

Medical Physics
Radiation Oncology
Radiosurgery

Background:

Accurate characterization of small stereotactic radiation fields is crucial but challenging.
Conical collimators are used for field shaping in stereotactic radiosurgery.
Limited commissioning data exists for small stereotactic fields.

Purpose of the Study:

To commission the cone dose calculation algorithm in a Varian Eclipse treatment planning system for a 5 mm cone.
To validate measurements against the Varian Golden Beam Data (GBD) and independent audit data.
To ensure accurate dose calculations for small stereotactic fields.

Main Methods:

Measurements of tissue maximum ratios (TMRs) and off-axis ratios (OARs) using microDiamond and SRS Diode detectors.
Output factor (OF) measurements using microDiamond and EBT-XD film.
Comparison of measured data with GBD, independent audit data, and IAEA TRS-483.
Film dosimetry for evaluating Eclipse dose calculations in phantoms.
Gamma analysis for comparing measured and calculated data.

Main Results:

Measured TMRs and OARs showed good agreement with GBD and passed gamma analysis.
Output factors measured with microDiamond and film were within measurement uncertainty.
Differences in OAR measurements were attributed to detector volume averaging.
Eclipse dose calculations were validated using film dosimetry in solid water and anthropomorphic head phantoms.

Conclusions:

The Varian 5 mm cone dose calculation algorithm was successfully commissioned in Eclipse.
The chosen configuration using microDiamond measured OF and SRS Diode measured TMR/OAR data was validated.
Accurate commissioning data is essential for reliable stereotactic radiosurgery treatment planning.