Related Experiment Video
Updated: Aug 31, 2025
03:50
Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
Published on: August 18, 2023
2.0K
Relationship between Depression and Constipation: Results from a Large Cross-sectional Study in Adults.
Peyman Adibi1, Maryam Abdoli2, Hamed Daghaghzadeh1
1Gastroenterology and Hepatology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Summary
Depression significantly increases the risk of functional constipation in adults. This association was observed in both genders but was notably stronger in men, highlighting the importance of mental health screening for gastrointestinal issues.
Area of Science:
- Gastroenterology
- Psychiatry
- Epidemiology
Background:
- Emerging evidence suggests a link between depression and functional constipation.
- This study investigates the association between depression and the risk of functional constipation, examining potential gender differences.
Purpose of the Study:
- To determine if depression is associated with an increased risk of functional constipation.
- To explore whether this association differs between men and women.
Main Methods:
- A cross-sectional study involving 3,362 adults aged 18-55 years.
- Functional gastrointestinal symptoms assessed using the modified Rome III questionnaire.
- Psychological health evaluated using the Hospital Anxiety and Depression Scale; depression defined as a score of 8 or higher.
Main Results:
- The prevalence of depression was 28.6% and constipation was 23.9%.
- Depressed individuals had a significantly higher risk of constipation (Adjusted Odds Ratio [AOR] = 1.69).
- The association between depression and constipation was stronger in men (AOR = 2.28) than in women (AOR = 1.55).
Conclusions:
- Depression is a significant risk factor for functional constipation.
- Mental health evaluations are crucial for patients with functional gastrointestinal disorders, especially those with constipation.
- The stronger association in men warrants further investigation into gender-specific mechanisms.
Related Concept Videos
01:18Depression: Overview
326
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
326
01:27Depressive Disorders: Etiology
159
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
159
01:27Depressive Disorders: MDD and Dysthymia
202
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
202
01:21Drugs for Treatment of Constipation-Predominant IBS
304
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
304
01:03Long-term Depression
2.6K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
2.6K
01:30Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
227
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
227