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A nanoplatform for mild-temperature photothermal and type I & II photodynamic therapy in the NIR-II biowindow
Bing Lu1, Zhecheng Zhang1, Yuying Huang1
1School of Chemistry and Chemical Engineering, Nantong University, Nantong, Jiangsu, 226019, P. R. China. 2020028lubing@ntu.edu.cn.
Abstract:
In the current work, we synthesized an A-D-A smallmolecule photosensitizer, denoted as DPTTIC, and a dual PEG-functionalized pillararene, denoted as WP5-8C-2PEG, and used them to construct novel DPTTIC nanoparticles (NPs) displaying NIR II absorption. Under 980 nm-wavelength laser irradiation, DPTTIC NPs performed well in mild-temperature photothermal and type I & II photodynamic anti-tumor therapy.
