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Yeast β-Glucans as Fish Immunomodulators: A Review
Cristian Machuca1, Yuniel Méndez-Martínez2, Martha Reyes-Becerril1
1Immunology & Vaccinology Group, Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz 23096, Mexico.
Animals : an Open Access Journal From MDPI
|August 26, 2022
Summary
Yeast beta-glucans can boost fish immunity against infections. This review explores recent research on yeast beta-glucans, highlighting their varied biological activities and potential in aquaculture.
Area of Science:
- Aquaculture
- Immunology
- Marine Biology
Background:
- Immunostimulants are used to prevent fish infections.
- Yeast beta-glucans are key compounds with immune-modulating properties.
- Commercial beta-glucans may be inefficient or cause adverse effects in some fish species.
Purpose of the Study:
- To review recent scientific reports on yeast beta-glucans in fish.
- To analyze the diverse biological activities of experimental beta-glucans.
- To assess the efficacy and potential of yeast beta-glucans in aquaculture.
Main Methods:
- Literature review of recent scientific reports.
- Analysis of studies on yeast beta-glucans in freshwater and marine fish.
- Examination of beta-glucan mechanisms, including cell receptor recognition.
Main Results:
- Yeast beta-glucans exhibit various biological activities beyond immune stimulation.
- Experimental beta-glucans show promise with antibacterial, antioxidant, and stress tolerance properties.
- Optimizing beta-glucan use requires considering species-specific responses and potential adverse effects.
Conclusions:
- Yeast beta-glucans offer a promising avenue for enhancing fish health and disease resistance.
- Further research into experimental beta-glucans can optimize their application in aquaculture.
- Understanding the specific properties of different yeast beta-glucans is crucial for effective immunostimulation.

