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Pulmonary Embolism Presenting with Pulmonary Infarction: Update and Practical Review of Literature Data
Giulia Gagno1, Laura Padoan2, Stefano D'Errico3
1Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI) and Department of Medical Surgical and Health Science, University of Trieste, 34149 Trieste, Italy.
Pulmonary infarction (PI), a consequence of pulmonary embolism (PE), is often underestimated. This review highlights diagnostic challenges and emphasizes improved protocols for accurate PI identification and management.
Area of Science:
- Cardiology
- Pulmonology
- Radiology
Background:
- Pulmonary infarction (PI) is a recognized complication of pulmonary embolism (PE).
- The incidence of PI is likely underestimated in non-fatal PE cases, with higher prevalence noted in postmortem studies.
- Current diagnostic challenges stem from overlapping symptoms with other conditions.
Purpose of the Study:
- To review the prevalence of PI in patients with PE.
- To identify predisposing factors for PI development.
- To summarize diagnostic tools and discuss clinical/prognostic implications.
Main Methods:
- Literature review of studies on pulmonary infarction and pulmonary embolism.
- Synthesis of data on PI prevalence, risk factors, and diagnostic modalities.
- Analysis of clinical and prognostic outcomes associated with PI.
Main Results:
- PI prevalence is significantly higher than typically reported, especially in postmortem analyses.
- Several predisposing factors contribute to PI development in PE patients.
- Radiological evaluation is standard, but emerging techniques like ultrasound and nuclear scanning show promise.
Conclusions:
- Accurate diagnosis of PI is crucial and often challenging.
- Improved diagnostic protocols integrating advanced imaging are needed.
- Understanding PI's implications is vital for patient management and prognosis.
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