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Updated: Aug 30, 2025
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Repeatability of new optical biometer and agreement with 2 validated optical biometers, all based on SS-OCT
Alice Galzignato1, Enrico Lupardi, Kenneth J Hoffer
1From the Studio Oculistico d'Azeglio, Bologna, Italy (Galzignato, Barboni); University Eye Clinic, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy (Lupardi); Stein Eye Institute, University of California, Los Angeles, California (Hoffer); St. Mary's Eye Center, Santa Monica, California (Hoffer); San Raffaele Hospital, Milan, Italy (Barboni); IRCCS G.B. Bietti Foundation, Rome, Italy (Schiano-Lomoriello, Savini).
Purpose:
To evaluate the repeatability of the measurements provided by a new optical biometer (EyeStar 900) based on swept-source optical coherence tomography (SS-OCT) and their agreement with the measurements given by 2 validated biometers based on the same technology, the IOLMaster 700 and Argos.
Setting:
IRCCS G.B. Bietti Foundation, Rome, Italy.
Design:
Prospective evaluation of diagnostic test.
Methods:
In a series of unoperated eyes, 3 consecutive scans were acquired with the EyeStar 900, and 1 with the IOLMaster 700 and the Argos. The following biometry parameters were analyzed: axial length (AL), keratometry (K), corneal astigmatism, central corneal thickness, corneal diameter (CD), anterior chamber depth (ACD), lens thickness (LT), and lens tilting. Repeatability was assessed using test-retest variability, the coefficient of variation (CoV), and the intraclass correlation coefficient (ICC); agreement was based on the 95% limits of agreement.
Results:
56 eyes of 56 patients were analyzed. High repeatability was achieved for all measured parameters, as the CoV was <1% in most cases and ICC was >0.95 for all parameters. Good to high agreement was found among the measurements of the 3 optical biometers, although some statistically significant differences were detected between the EyeStar 900 and Argos (mean K, ACD, LT, and CD were higher with the Argos). The Argos measured a shorter AL in eyes >25 mm.
Conclusions:
The new generation SS-OCT EyeStar 900 optical biometer produces highly repeatable measurements that are in good agreement with those provided by 2 previously validated instruments.
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