Related Experiment Video

Updated: Aug 30, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions

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A new role for Hif-1α.

Mingyu Shin1, Jiwon Shim1,2,3

  • 1Department of Life Sciences, Hanyang University, Seoul, Republic of Korea.

Elife
|August 30, 2022
PubMed
Summary

A gene typically responding to low oxygen (hypoxia) surprisingly protects insect muscles during long migratory flights without needing oxygen. This discovery reveals a new role for hypoxia-response genes in muscle resilience.

Keywords:
alternative splicinganimal flightcell biologydj-1energy metabolismhypoxia inducible factorredox homeostasis

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