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Updated: Aug 30, 2025

Fluorescent Leakage Assay to Investigate Membrane Destabilization by Cell-Penetrating Peptide
Published on: December 19, 2020
Highlights from Faraday discussion 232: Peptide-membrane interactions, 8th-10th September 2021 (online)
1CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India. sp965@cornell.edu.
Abstract:
The Faraday discussions meeting on peptide-membrane interactions was designed with the goal of repositioning peptides as powerful model systems that are indispensable in contemporary membrane biophysics and biology research. The meeting, originally scheduled for September 2020, was finally held in a virtual format during September 8th-10th, 2021 due to the COVID-19 pandemic. The meeting saw enthusiastic participation by ∼120 scientists from 23 countries. There were 23 talks delivered during the four sessions and 25 posters presented in two poster sessions (the published volume can be accessed online). The meeting drew attention to the multitude of open questions that persist in our understanding of the behavior of membrane peptides and proteins in spite of nearly half-a-century of intensive interdisciplinary research, and was beyond successful in throwing into sharp relief the enduring relevance of exploring membrane biophysics and biology through the looking glass of peptide-membrane interactions.
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