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Updated: Aug 29, 2025

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Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
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Topical Review: Contact Lens Eye Health and Safety Considerations in Government Policy Development.
Carol Lakkis, Kathrine Osborn Lorenz1, Michael Mayers1
1Johnson and Johnson Vision Care, Inc., Jacksonville, Florida.
Summary
Patient safety during contact lens wear is crucial. Regular eye care professional visits and prescribed lenses reduce risks of sight-threatening events and significant healthcare costs from ocular infections.
Area of Science:
- Ophthalmology and Public Health Policy
Background:
- Contact lenses are regulated as medical devices by the Food and Drug Administration (FDA).
- The contact lens market and eye health landscape are rapidly evolving, influenced by new federal and state policies.
- The U.S. Federal Trade Commission (FTC) recently updated the Contact Lens Rule, impacting market dynamics.
Purpose of the Study:
- To compile and review data on contact lens-related adverse events.
- To analyze the economic impact of these adverse events on the healthcare system.
- To inform government policy development regarding contact lens safety and regulation.
Main Methods:
- Clinical perspective compilation and review of existing data.
- Analysis of contact lens-related adverse events and their economic burden.
- Examination of patient risk factors, including adherence to professional eye care.
Main Results:
- Contact lens wear can lead to adverse events, from mild discomfort to severe microbial keratitis.
- Patients not seeing eye care professionals regularly or obtaining prescribed lenses face higher risks.
- Annual economic burden of contact lens-related microbial keratitis in the U.S. is estimated at $175 million.
Conclusions:
- Emphasizing patient health and safety in contact lens wear is paramount.
- The value of the eye care professional-patient relationship is critical for mitigating risks.
- Continued professional oversight is essential for safeguarding consumers in the evolving contact lens market.
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