Related Experiment Video
Updated: Aug 29, 2025

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
Published on: February 23, 2020
Towards the 2D velocity reconstruction in abdominal aorta from Color-Doppler Ultrasound
Maria Nicole Antonuccio1, Hernan G Morales2, Alexandre This2
1Philips Research Paris, 92150 Suresnes, France; BioCardioLab, Bioengineering Unit - Heart Hospital, Fondazione Toscana "G. Monasterio", 54100 Massa, Italy; Mines Saint-Étienne, Univ Lyon, Univ Jean Monnet, INSERM, U 1059 Sainbiose,F - 42023 Saint-Étienne, France.
Abstract:
Magnetic resonance imaging (MRI) is the preferred modality to assess hemodynamics in healthy and diseased blood vessels. As an affordable and non-invasive alternative, Color-Doppler imaging is a good candidate. Nevertheless, Color-Doppler acquisitions provide only partial information on the blood velocity within the vessel. We present a framework to reconstruct 2D velocity fields in the aorta. We generated 2D Color-Doppler-like images from patient-specific Computational Fluid Dynamics (CFD) models of abdominal aortas and evaluated the framework's performance. The 2D velocity field reconstruction is based on the minimization of a cost function, in which the reconstructed velocities are constrained to satisfy fluid dynamics principles. The numerical evaluations show that the reconstructed vector flow fields agree with ground-truth velocities, with an average magnitude error of less than 4% and an average angular error of less than 2∘. We lastly illustrate the 2D velocity field reconstructed from in-vivo Color-Doppler data. Observing the hemodynamics in patients is expected to have a clinical impact in assessing disease development and progression, such as abdominal aortic aneurysms.

