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[Orbital Rosai-Dorfman disease: a case report]
1Department of Ophthalmology, the Second Affiliated Hospital of Navy Military Medical Hospital, Shanghai 200003, China.
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|September 7, 2022
Summary
Orbital Rosai-Dorfman disease caused bilateral eyelid swelling and lacrimal gland enlargement in a young patient. Surgical removal of the orbital masses led to a good outcome with no recurrence during follow-up.
Area of Science:
- Ophthalmology
- Pathology
- Radiology
Background:
- Rosai-Dorfman disease (RDD) is a rare benign proliferative disorder.
- Orbital involvement of RDD is uncommon, particularly in young individuals.
- Eyelid and lacrimal gland masses can present diagnostic challenges.
Observation:
- A 19-year-old patient presented with chronic bilateral eyelid swelling.
- Physical examination revealed active masses in the upper eyelid and lacrimal gland areas.
- Orbital MRI demonstrated significant bilateral lacrimal gland enlargement, more pronounced on the left.
Findings:
- Histopathological examination confirmed orbital Rosai-Dorfman disease.
- Surgical excision of the orbital masses was performed twice.
- The patient experienced no tumor recurrence during a three-month follow-up period.
Implications:
- This case highlights the importance of considering Rosai-Dorfman disease in the differential diagnosis of orbital masses presenting with eyelid swelling.
- Early diagnosis and appropriate management are crucial for favorable outcomes in orbital RDD.
- Multidisciplinary collaboration between ophthalmology, pathology, and radiology is essential for managing complex orbital conditions.

