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Global research trends in atherosclerosis: A bibliometric and visualized study
Wende Tian1,2,3, Tai Zhang1,2,4, Xinyi Wang1,2,3
1Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Frontiers in Cardiovascular Medicine
|September 9, 2022
Summary
This bibliometric analysis reveals the United States leads atherosclerosis research, with a focus on inflammation, NLRP3 inflammasome, and gut microbiota. Key research areas include exosomes and cellular senescence.
Area of Science:
- Cardiovascular Research
- Bibliometrics
- Biomedical Science
Background:
- Atherosclerosis research is rapidly evolving, necessitating a comprehensive overview of the scientific literature.
- Bibliometric analysis provides a quantitative approach to map the research landscape and identify trends.
Purpose of the Study:
- To conduct a bibliometric analysis of atherosclerosis research.
- To identify key contributors, publications, and emerging research themes.
Main Methods:
- Searched Web of Science Core Collection (2012-2022) for atherosclerosis articles and reviews.
- Utilized CiteSpace and VOSviewer for bibliometric analysis, including co-citation and keyword analysis.
- Analyzed publication productivity by country, institution, author, and journal.
Main Results:
- 20,014 publications were analyzed, with the United States as the most productive country.
- Johns Hopkins University and ALVARO ALONSO were the most prolific institution and author, respectively.
- Key research terms included NLRP3 inflammasome, short-chain fatty acids (SCFAs), and exosomes.
Conclusions:
- North America and Europe dominate atherosclerosis research.
- Inflammation, NLRP3 inflammasome, gut microbiota, SCFAs, exosomes, and cellular senescence are current hot topics.
- The study maps the intellectual structure and identifies future research directions in atherosclerosis.
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