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Imaging of Macrocephaly

Ilana Neuberger1, Nicholas V Stence1, John A Maloney1

  • 1Department of Radiology, Children's Hospital Colorado, University of Colorado, 13123 East 16th Avenue, Box 125 Aurora, CO 80045, USA.

Clinics in Perinatology
|September 16, 2022
PubMed

Insights

Macrocephaly, an enlarged head in infants, has many causes. Neuroimaging is crucial for diagnosing infantile macrocephaly and guiding treatment by identifying key findings.

Area of Science:

  • Pediatric Neurology
  • Neuroradiology
  • Medical Imaging

Background:

  • Macrocephaly is a frequent diagnosis in infants.
  • Causes range from benign to malignant conditions.
  • Accurate diagnosis is essential for appropriate clinical management.

Purpose of the Study:

  • To review distinct and prevalent neuroimaging findings in macrocephalic infants.
  • To correlate imaging findings with potential etiologies.
  • To aid in the diagnostic process for infantile macrocephaly.

Main Methods:

  • Literature review of neuroimaging studies in macrocephalic infants.
  • Analysis of common and distinct imaging patterns.
  • Categorization of findings based on etiology.

Main Results:

  • Identification of key neuroimaging features associated with various causes of macrocephaly.
  • Emphasis on the role of imaging in differentiating benign from serious conditions.
  • Highlighting specific patterns indicative of genetic, infectious, or neoplastic etiologies.

Conclusions:

  • Neuroimaging is indispensable for evaluating infantile macrocephaly.
  • Recognizing specific imaging findings aids in timely diagnosis and management.
  • This review provides a guide to prevalent neuroimaging findings in the macrocephalic infant.

Keywords:
Abusive head traumaHydrocephalusMacrocephalyMegalencephaly

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