Related Experiment Video
Updated: Aug 28, 2025
08:12
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
1.7K
Artificial chordae for mitral valve repair.
Igor Vendramin1, Aldo D Milano2, Angela Pucci3
1Cardiothoracic Department, University Hospital, Udine, Italy.
Journal of Cardiac Surgery
|September 18, 2022
Summary
Rupture of artificial neo-chordae can cause mitral regurgitation after valve repair. While rare, this complication necessitates careful patient follow-up to ensure durable repair stability.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
Background:
- Mitral valve repair using expanded polytetrafluoroethylene (ePTFE) neo-chordae is common.
- The failure rate of ePTFE neo-chordae leading to recurrent mitral regurgitation is not well-established.
Purpose of the Study:
- To define the incidence and characteristics of neo-chordae failure after mitral valve repair.
- To identify potential causes and pathological findings associated with ePTFE neo-chordae complications.
Main Methods:
- Systematic review of reported complications following mitral valve repair with neo-chordae.
- Literature search conducted via PubMed, Medline, and Google Scholar.
Main Results:
- Identified 26 cases of ePTFE neo-chordae rupture, often reported as isolated incidents.
- Pathological findings revealed consistent neo-chordae pliability and length, with rupture linked to suture size; calcification and infection were rare.
- Some recurrent mitral regurgitation cases were attributed to technical errors rather than neo-chordal failure.
Conclusions:
- Artificial neo-chordae offer durable mitral valve repair with excellent late results.
- Late chordal rupture can occur, leading to reoperation for mitral regurgitation, though it is a rare complication.
- Patients undergoing mitral valve repair with artificial neo-chordae require vigilant follow-up for potential late complications.
More Related Videos
Related Concept Videos
01:27Mitral Valve Prolapse I: Introduction
34
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
34
01:25Mitral Regurgitation III: Medical Management
25
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
25
01:26Mitral Stenosis III: Medical Management
18
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
18
01:20Mitral Regurgitation I: Introduction
36
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
36
01:22Mitral Stenosis I: Introduction
28
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
28
01:22Mitral Valve Prolapse II: Assessment and Management
39
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
39