Related Experiment Video
Updated: Aug 28, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
Implementation and outcome evaluations of a multi-site improvement program in cancer genetics
Erica M Bednar1,2, Blake Harper1,3, Michael T Walsh1,3
1Cancer Prevention and Control Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
This cancer genetics quality improvement program successfully disseminated across five sites, showing high fidelity and improved participant knowledge and skills. Implementation challenges were noted, but overall outcomes were positive.
Area of Science:
- Health Services Research
- Quality Improvement Science
- Cancer Genetics Implementation Science
Background:
- Disseminating clinical programs requires robust evaluation to understand successes and challenges.
- Cancer genetics services benefit from structured quality improvement (QI) initiatives.
- Virtual facilitation can support multi-site QI implementation.
Purpose of the Study:
- To evaluate the implementation and initial outcomes of a multi-site cancer genetics QI program.
- To assess program delivery, fidelity, and participant-reported outcomes.
- To identify implementation facilitators and barriers in diverse health systems.
Main Methods:
- A logic model guided the evaluation of program implementation and outcomes.
- Data collection included program documents and an Evaluation Survey of 21 participants.
- Descriptive statistics were used to analyze implementation data and participant feedback.
Main Results:
- The program was delivered with high fidelity, with all inputs, activities, and outputs meeting expectations.
- Participants reported significant improvements in QI knowledge, perceived importance and feasibility, and self-efficacy.
- Intermediate outcomes such as barrier identification and improved teamwork were achieved.
Conclusions:
- The genetic counselor-led, virtually facilitated cancer genetics QI program was successfully implemented across multiple sites.
- The program demonstrated high fidelity and led to significant improvements in short-term and intermediate outcomes.
- Future research should focus on long-term, patient-level outcomes.
More Related Videos
10:27Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
Published on: July 25, 2020
13:24Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
Published on: April 11, 2016
Related Concept Videos
Cancer Survival Analysis
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Treatment Resistant Cancers