Related Experiment Video
Updated: Aug 27, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Exploring integrated threshold concept knowledge as a route to understanding the epistemic nature of the
Kim M Mitchell1, Marlo Pereira-Edwards2
1Coordinator Research, Scholarship, and Quality Assurance, Nursing Department, Red River College Polytechnic, C608-2055 Notre Dame Ave., Winnipeg, Manitoba R3H 0J7, Canada.
Background:
An evidence-based practice (EBP) mindset is the embodiment of the belief that a professional nursing identity requires consideration of research evidence in all practice encounters. Historical tensions between research and practice have contributed to practitioner and student resistance to research knowledge. Examining the troublesome nature of learning research may facilitate the development of teaching strategies to enhance the uptake of research in practice.
Aim:
To use Timmermans and Meyer's Integrated Threshold Concept Knowledge Framework to explore the troublesome nature of learning research and evidence-based practice and identify how threshold concepts of EBP can be leveraged to understand the epistemic nature of the evidence-based practice mindset.
Methods:
A multimethod case analysis using a triangulated approach was applied to 169 written artifacts from 61 nursing students. Written artifacts included course assignments and a learning survey that were examined to identify troublesome EBP concepts.
Results:
Threshold concepts of EBP are leveled as foundational, application, or epistemic, with some concepts acting as prerequisites to others. Epistemic threshold concepts include awakening to the importance of research to nursing practice and discursive ability with research and EBP concepts.
Conclusion:
Understanding the epistemic nature of EBP knowledge may be a route to identifying the most effective pedagogies to simulate transformative and irreversible EBP threshold concept knowledge. EBP concepts require mindful threading in nursing curriculums to startle students into epiphanies about the importance of research to practice.
More Related Videos
Related Concept Videos
Critical Thinking II
Critical Thinking
Colleges and universities are...
Critical Thinking I
Patient-centered Care
Reason and Intuition
The Scientific Method in Nursing Process
When using research findings to change practice, one must understand the process used to guide a study. The scientific method is a systematic, step-by-step process that supports the data's validity, reliability, and generalizability. As a result, findings can be...

