Related Experiment Video
Updated: Aug 27, 2025
Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
Published on: February 16, 2011
Adverse Childhood Experiences in Patients With Neurologic Disease
Adys Mendizabal1, Cody L Nathan1, Pouya Khankhanian1
1Department of Neurology (AM), University of California Los Angeles (UCLA); Department of Neurology (CLN), Northwestern University Memorial Hospital, Chicago, IL; Department of Neurology (PK), Kaiser Permanente Walnut Creek Medical Center, Walnut Creek, CA; Department of Neurology (MA), Children's Hospital of Philadelphia (CHOP); Department of Neurology (CC, AA-B, ND), Hospital of the University of Pennsylvania; and Perlman School of Medicine at the University of Pennsylvania (LB), Philadelphia.
Neurology patients exhibit higher rates of adverse childhood experiences (ACEs) compared to the general population. These high ACE scores correlate with increased healthcare use and more medical and psychiatric conditions.
Area of Science:
- Neurology
- Psychiatry
- Public Health
Background:
- Adverse Childhood Experiences (ACEs) are linked to negative health outcomes.
- Prevalence and impact of ACEs in neurology patient populations are not well-defined.
Purpose of the Study:
- To determine the prevalence of high ACE scores in neurology outpatients.
- To investigate the association between high ACE scores and healthcare utilization, and comorbid conditions.
Main Methods:
- Cross-sectional study of 198 neurology outpatients.
- ACE questionnaire, depression/anxiety screenings, and healthcare utilization data collected.
- Statistical analysis adjusted for age, sex, and race/ethnicity.
Main Results:
- Neurology patients had a higher prevalence of high ACE scores (23.7%) than US population estimates (12.6%).
- High ACE scores were significantly associated with increased emergency department visits, hospitalizations, and telephone encounters.
- High ACE scores correlated with increased medical/psychiatric comorbidities and higher depression/anxiety scores.
Conclusions:
- Neurology patients have a higher prevalence of high ACEs.
- High ACEs are associated with greater healthcare utilization and comorbidities in this population.
- Addressing ACEs may improve health outcomes for neurology patients.
More Related Videos
04:20Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
Published on: July 12, 2024
09:49Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Related Concept Videos
01:28Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
01:21Factors Affecting Drug Response: Overview
01:12Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
01:27Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
01:30Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...