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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

628
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Video

Updated: Aug 27, 2025

Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
06:19

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Published on: May 31, 2024

963

Effects of COVID-19 on Intravitreal Injection Clinic After Lockdown.

Terry Hsieh1, Bradley S Gundlach2, Sahar Ashrafzadeh2

  • 1Stein Eye Institute, University of California, Los Angeles, CA, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|September 26, 2022
PubMed
Summary

Intravitreal injection clinic volume returned to pre-COVID levels post-lockdown, but high-risk patients with comorbidities did not return for essential eye injections.

Keywords:
age-related macular degenerationanti-vascular endothelial growth factorco-morbiditiescoronavirusdiabetic retinopathyretina

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Area of Science:

  • Ophthalmology
  • Public Health
  • Retinal Diseases

Background:

  • The COVID-19 pandemic necessitated public health measures, including lockdowns, significantly disrupting routine healthcare services.
  • Intravitreal injections are critical for managing various retinal diseases, and disruptions in care can lead to vision loss.

Purpose of the Study:

  • To assess the recovery of patient volume at an intravitreal injection clinic following the COVID-19 lockdown.
  • To identify patient demographics and comorbidities associated with return rates to the clinic.

Main Methods:

  • A retrospective review of electronic medical records at a Veterans Health Administration (VHA) tertiary care clinic in Los Angeles County.
  • Comparison of clinic volumes and patient characteristics during three periods: pre-pandemic (2019), COVID-19 lockdown, and post-lockdown (2020).
  • Statistical analyses included one-way ANOVA and generalized estimating equation multivariate analysis.

Main Results:

  • Intravitreal injection clinic volume returned to 98.9% of pre-lockdown levels immediately after restrictions eased, closely matching pre-pandemic volumes.
  • Patients with chronic obstructive pulmonary disease (COPD) and organ transplant recipients were less likely to receive injections post-lockdown.
  • The proportion of patients receiving injections for cancer and diabetic macular edema (DME) increased post-lockdown.

Conclusions:

  • Intravitreal injection clinic attendance rapidly recovered to pre-pandemic levels after lockdown.
  • Certain patient groups with high-risk comorbidities, such as COPD and organ transplant recipients, showed reduced clinic return rates.
  • Targeted outreach and enhanced safety measures may be necessary for specific patient populations to ensure continuity of ophthalmic care.